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Publikationsliste - 2020



Originalarbeiten in wissenschaftlichen Fachzeitschriften

Jahre: 2020
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    2020


    • Moumbock AFA, Gao M, Qaseem A, Li J, Kirchner PA, Ndingkokhar B, Bekono BD, Simoben CV, Babiaka SB, Malange YI, Sauter F, Zierep P, Ntie-Kang F, Günther S
      StreptomeDB 3.0: an updated compendium of streptomycetes natural products.
      2020 Nucleic Acids Res
    • Simoben CV, Qaseem A, Moumbock AFA, Telukunta KK, Günther S, Sippl W, Ntie-Kang F
      Pharmacoinformatic Investigation of Medicinal Plants from East Africa.
      2020 Mol Inform
    • Roddan T, Sula A, Mendez-Sanchez D, Subrizi F, Lichman B, Broomfield J, Richter M, Andexer JN, Ward J, Keep N, Hailes HC
      Single-step syntheses of (1S)-aryl-tetrahydroisoquinolines by norcoclaurine synthases,
      2020 Chem Commun
    • Stockinger P, Roth S, Müller M, Pleiss J
      Systematic evaluation of imine-reducing enzymes: common principles in imine reductases, β hydroxyacid dehydrogenases, and short-chain dehydrogenases/reductases
      2020 Chembiochem, Band: 21, Seiten: 2689 - 2695
    • Hüttel W, Müller M
      Regio- and Stereoselective Intermolecular Phenol Coupling Enzymes in Secondary Metabolite Biosynthesis
      2020 Nat Prod Rep
    • Herrlinger E-M, Hau M, Redhaber DM, Greve G, Willmann D, Steimle S, Müller M, Lübbert M, Miething CC, Schüle R, Jung M
      Nitroreductase-Mediated Release of Inhibitors of Lysine-Specific Demethylase 1 (LSD1) from Prodrugs in Transfected Acute Myeloid Leukaemia Cells
      2020 Chembiochem, Band: 21, Seiten: 2329 - 2347
    • Thiele W, Froede R, Steglich W, Müller M
      Isolation, Structure Elucidation, and Enzymatic Formation of Rufoschweinitzin, a Binaphthalene from the Basidiomycete Cortinarius rufoolivaceus
      2020 Chembiochem, Band: 21, Seiten: 1423 - 1427
    • Husain SM, Präg A, Linnenbrink A, Bechthold A, Müller M
      Insights into the Role of Ketoreductases in the Biosynthesis of Bacterial Aromatic Polyketides Such As GTRI-02
      2020 Chembiochem, Band: 21, Seiten: 780 - 784
    • Obermaier S, Müller M
      Ibotenic acid biosynthesis in the fly agaric is initiated by glutamate hydroxylation
      2020 Angew Chem Int Edit, Band: 59, Seiten: 12432 - 12435
    • Roth S, Stockinger P, Steff J, Steimle S, Sautner V, Tittmann K, Pleiss J, Müller M
      Crossing the Border: From Keto- to Imine Reduction in Short-Chain Dehydrogenases/Reductases
      2020 Chembiochem, Band: 21, Seiten: 2615 - 2619
    • Thiele W, Obermaier S, Müller M
      A Fasciclin Protein is Essential for Selective Phenol-Coupling in Sporandol Biosynthesis
      2020 Acs Chem Biol, Band: 15, Seiten: 844 - 848
    • Kreisel W, Schaffner D, Lazaro A, Trebicka J, Merfort I, Schmitt-Graeff A, Deibert P
      Phosphodiesterases in the Liver as Potential Therapeutic Targets of Cirrhotic Portal Hypertension.
      2020 Int J Mol Sci, Band: 21, Nummer: 17
    • Calderón C, Rubarth L, Cebo M, Merfort I, Lämmerhofer M
      Lipid Atlas of Keratinocytes and Betulin Effects on its Lipidome Profiled by Comprehensive UHPLC-MS/MS with Data Independent Acquisition Using Targeted Data Processing.
      2020 Proteomics, Band: 20, Nummer: 11, Seiten: e1900113 - e1900113
    • Schiedel M, Lehotzky A, Szunyogh S, Oláh J, Hammelmann S, Wössner N, Robaa D, Einsle O, Sippl W, Ovádi J, Jung M
      HaloTag-Targeted Sirtuin Rearranging Ligand (SirReal) for theDevelopment of Proteolysis Targeting Chimeras (PROTACs) Against theLysine Deacetylase Sirtuin 2 (Sirt2)
      2020 ChemRxiv
    • Saraswati AP, Relitti N, Brindisi M, Osko JD, Chemi G, Federico S, Grillo A, Brogi S, McCabe NH, Turkington RC, Ibrahim O, O'Sullivan J, Lamponi S, Ghanim M, Kelly VP, Zisterer D, Amet R, Hannon P, Vanni F, Ulivieri C, Herp D, Di Costanzo A, Saccoccia F, Ruberti C, Jung M, Altucci L, Gemma S, Butini S, Christianson D, Campiani G
      Spiroindoline-capped selective HDAC6 inhibitors: Design, Synthesis, Structural Analysis and Biological Evaluation
      2020 Acs Med Chem Lett
    • Glas C, Dietschreit JCB, Wössner N, Urban L, Ghazy E, Sippl W, Jung M, Ochsenfeld C, Bracher F
      Identification of the subtype-selective Sirt5 inhibitor balsalazide through systematic SAR analysis and rationalization via theoretical investigations.
      2020 Eur J Med Chem, Band: 206, Seite: 112676
    • Zalba S, Seynhaeve A L B, Brouwers J F, Süss R, Verheij M, ten Hagen T L M
      Sensitization of drug resistant sarcoma tumors by membrane modulation via short chain sphingolipid-containing nanoparticles
      2020 Nanoscale, Band: 12, Seiten: 16967 - 16979
    • Kaiser L, Weinschrott H, Quint I, Blaess M, Csuk R, Jung M, Kohl M, Deigner H-P
      Metabolite patterns in human myeloid hematopoiesis result from lineage-dependent active metabolic pathways
      2020 Int J Mol Sci
    • Reiner D, Seifert L, Deck C, Schüle R, Jung M, Stark H
      Epigenetics meets GPCR – Inhibition of histone H3 methyltransferase (G9a) and histamine H3 receptor for Prader-Willi Syndrome
      2020 Sci Rep-uk
    • Brosowsky J, Lutterbeck M, Liebich A, Keller M, Herp D, Vogelmann A, Jung M, Breit B
      Syntheses of Thailandepsin B Pseudo-Natural Products: Access to new highly potent HDAC Inhibitors via Late Stage Modification
      2020 Chem-eur J
    • Li J, Moumbock A F, Günther S
      Exploring co-crystallized aromatic cage binders to target histone methylation reader proteins
      2020 J Chem Inf Model, Band: xxx, Nummer: xxx, Ergänzungsband: xxx, Seiten: xxx - xxx
    • Hartl FA, Beck-Garcìa E, Woessner NM, Flachsmann LJ, Cárdenas RMV, Brandl SM, Taromi S, Fiala GJ, Morath A, Mishra P, Yousefi OS, Zimmermann J, Hoefflin N, Köhn M, Wöhrl BM, Zeiser R, Schweimer K, Günther S, Schamel WW, Minguet S
      Noncanonical binding of Lck to CD3ε promotes TCR signaling and CAR function.
      2020 Nat Immunol, Band: 21, Nummer: 8, Seiten: 902 - 913
    • Mordhorst S, Andexer JN
      Round, Round We Go – Strategies for Enzymatic Cofactor Regeneration
      2020 Nat Prod Rep
    • Strohmeier GA, Schwarz A, Andexer JN, Winkler M
      Co-factor demand and regeneration in the enzymatic one-step reduction of carboxylates to aldehydes in cell-free systems
      2020 J Biotechnol, Band: 307, Seiten: 202 - 207
    • Markones M, Fippel A, Kaiser M, Drechsler C, Hunte C, Heerklotz H
      Stairway to Asymmetry: Five Steps to Lipid-Asymmetric Proteoliposomes
      2020 Biophys J, Band: 118, Nummer: 2, Seiten: 294 - 302
    • Stulz A, Breitsamer M, Winter G, Heerklotz H
      Primary and secondary binding of exenatide to liposomes
      2020 Biophys J, Band: 118, Nummer: 3, Seiten: 600 - 611
    • Liang S, Fuchs S, Mymrikov E V, Stulz A, Kaiser M, Heerklotz H, Hunte C
      Calcium Affects CHP1 and CHP2 Conformation and Their Interaction With sodium/proton Exchanger 1
      2020 Faseb J, Band: 34, Nummer: 2, Seiten: 3253 - 3266
    • Ghazy E, Zeyen P, Herp D, Hügle M, Schmidtkunz K, Erdmann F, Robaa D, Schmidt M, Morales ER, Romier C, Günther S, Jung M, Sippl W
      Design, synthesis, and biological evaluation of dual targeting inhibitors of histone deacetylase 6/8 and bromodomain BRPF1.
      2020 Eur J Med Chem, Band: 200, Seiten: 112338 - 112338
    • Trenk D
      xxx
      2020 Ann Intern Med, Band: 172, Nummer: 11, Seiten: 1 - 5
    • Schiedel M, Daub H, Itzen A, Jung M
      Validation of Slow Off-Kinetics of Sirtuin Rearranging Ligands (SirReals) by Means of the Label-Free Electrically Switchable Nanolever Technology
      2020 Chembiochem, Band: 21, Seiten: 1161 - 166
    • Kalinin DV, Shaik TB, Jana SK, Pfafenrot M, Chakrabarti A, Melesina J, Sippl W, Romier C, Jung M, Holl R
      Triazole-based smHDAC8 Inhibitors: Synthesis and Biological Evaluation
      2020 Chemmedchem, Band: 15, Seiten: 571 - 584
    • Saccoccia F, Brindisi M, Gimmelli R, Relitti N, Alessandra A, Saraswati AP, Cavella C, Brogi S, Chemi G, Butini S, Papoff G, Senger J, Herp D, Jung M, Campiani G, Gemma S, Ruberti G
      Screening and phenotypical characterization of Schistosoma mansoni histone deacetylase 8 (SmHDAC8) inhibitors as multi-stage antischistosomal agents
      2020 Acs Infect Dis, Band: 6, Seiten: 100 - 113
    • Osko JD, Porter NJ, Reddy PAN, Xiao Y-C, Rokka J, Jung M, Hooker JM, Salvino JM, Christianson DW
      Exploring structural determinants of inhibitor affinity and selectivity in complexes with Histone Deacetylase 6
      2020 J Med Chem, Band: 63, Seiten: 295 - 308
    • Westphal M, Sant P, Jung M, Hauser A-T, Driever W
      Chemical genetics screen identifies epigenetic mechanisms involved in dopaminergic and noradrenergic neurogenesis in zebrafish
      2020 Front Genet, Band: 11, Seite: 80
    • Grathwol CW, Wössner N, Behnisch-Cornwell S, Schulig L, Jung M, Link A
      Activation of Sirt2 inhibitors employing photoswitchable geometry and aqueous solubility
      2020 Chemmedchem
    • Ghazy E, Zeyen P, Herp D, Hügle M, Schmidtkunz K, Erdmann F, Robaa D, Schmidt M, Morales ER, Romier C, Günther S, Jung M, Sippl W
      Design, synthesis, and biological evaluation of dual targeting inhibitors of histone deacetylase 6/8 and bromodomain BRPF1
      2020 Eur J Med Chem
    • Wössner N, Alhalabi Z, Gonzalez Nieto J, Swyter S, Gan J, Schmidtkunz K, Zhang L, Ovaa H, Einsle O, Vaquero A, Sippl W, Jung M
      Si1th (Sirtuin 1 Inhibiting Thiocyanates) – a new class of selective Sirt1 inhibitors
      2020 Front Oncol
    • Doring K, Qaseem A, Becer M, Li J, Mishra P, Gao M, Kirchner P, Sauter F, Telukunta KK, Moumbock AFA, Thomas P, Gunther S
      Automated recognition of functional compound-protein relationships in literature.
      2020 Plos One, Band: 15, Nummer: 3, Seiten: e0220925 - e0220925

    Reviews/Übersichtsartikel in wissenschaftlichen Fachzeitschriften

    Jahre: 2020
    Icon: top zurück zur Übersicht aller Publikationen

      2020


      • Vogelmann A, Robaa D, Sippl W, Jung M
        Epigenetic PROTACs
        2020 Curr Opin Chem Biol, Band: 57, Seiten: 8 - 16

      Buchbeiträge

      Jahre: 2020
      Icon: top zurück zur Übersicht aller Publikationen

        2020


        • Sudar M, Walter A, Müller M, Blažević ZF
          MenD-catalyzed Synthesis of 6-Cyano-4-oxohexanoic Acid, in Practical Methods for Biocatalysis and Biotransformations 4/Applied Biocatalysis
          In: The Chemist's Enzyme Toolkit
          2020, Wiley, John Whittall, Peter J. Sutton, John Whittall, Peter J. Sutton,

        Sonstige Publikationen

        Jahre: 2020
        Icon: top zurück zur Übersicht aller Publikationen

          2020


          • Andexer JN, Rentmeister A
            Challenging nature’s preference for methylation
            Nat Chem, Seiten: 791 - 782, 2020
          • Andexer JN, Hüttel W
            Trendberichte 2019: Enzymreaktionen
            , Band: 68, Seiten: 69 - 70, 2020
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